A multiscale, spatially distributed model of asthmatic airway hyper-responsiveness
نویسندگان
چکیده
منابع مشابه
Static and dynamic stress heterogeneity in a multiscale model of the asthmatic airway wall.
Airway hyperresponsiveness (AHR) is a key characteristic of asthma that remains poorly understood. Tidal breathing and deep inspiration ordinarily cause rapid relaxation of airway smooth muscle (ASM) (as demonstrated via application of length fluctuations to tissue strips) and are therefore implicated in modulation of AHR, but in some cases (such as application of transmural pressure oscillatio...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2010
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2010.07.032